| A Quick Look at Carbohydrate
Quality
Because of the harmful effects of carbohydrates of blood sugar
control, some popular diets have led people to believe that the
best way to eat is to avoid carbohydrates almost entirely. I don't
agree with this approach. In fact, based upon results from short-term
clinical trials as well as large population-based based studies,
diets that have a higher intake of quality carbohydrates are consistently
associated with lower risk for diabetes, obesity, cancer and heart
disease. The best approach is to focus on quality carbohydrate sources
using the glycemic index and the glycemic load index.
The Glycemic Index
The glycemic index (GI) refers to how quickly blood sugar levels
will rise after eating a certain type of food. To determine a food's
GI rating, measured portions of the food containing 50 grams of
carbohydrate are fed to at least 10 healthy people after an overnight
fast. For example, to test boiled spaghetti, the scientists give
their subjects 200 grams of spaghetti, which according to standard
food composition tables provide 50 grams of available carbohydrate.
Finger-prick blood samples are taken at 15-30 minute intervals over
the next two hours to construct a blood sugar response curve. The
area under the curve (AUC) is calculated and reflects the total
rise in blood sugar (glucose) levels after eating the test food.
The scientists compare this response with the volunteer's response
to a reference food, which may be either glucose or white bread.
The GI rating of the test food is calculated by dividing the AUC
for the test food by the AUC for the reference food (white bread
or glucose) and multiplying by 100. The average of the GI ratings
from all ten subjects is published as the GI of that food. Foods
with a lower glycemic index will create a slower rise in blood sugar,
and foods with a higher glycemic index will create a faster rise
in blood sugar.
Clinical Research with the Glycemic
Index
Evidence from clinical studies also shows that replacing high-glycemic-index
carbohydrates with a low-glycemic-index carbohydrate sources will
improve blood sugar control. Simply replacing products made with
white flour and potatoes with whole grain, minimally refined products
can have dramatic impact on improving blood sugar levels and is
associated with a lower risk for both diabetes and cardiovascular
disease. One of the key reasons may be the whole grain foods are
rich in magnesium while this vital nutrient has been stripped away
in refined flour. In one analysis, the protective effect of whole
grain consumption was lost when the relative risk was adjusted for
magnesium intake.
To provide some general guidelines, here is a chart listing various
foods and their glycemic index classification.
Table 1 -
Classification of Foods by Glycemic Index Scores
| Fruits
& Vegetables |
|
Grains,
Nuts, Legumes |
| Very
High |
High |
Medium |
Low |
Very
High |
High |
Medium |
Low |
| |
|
|
|
|
|
|
|
| none |
Banana
Raisins, dates, and other dried fruits
Beets
Potato and other starchy vegetables
Orange
Orange Juice
Peach
Pineapple
Watermelon |
Cantaloupe
Grapes |
Apple
Apricot
Asparagus
Broccoli
Brussel Sprouts
Cauliflower
Celery
Cherries
Cucumber
Grapefruit
Green Beens
Green Pepper
Lettuce
Mushrooms
Onions
Plums
Spinach
Strawberries
Tomato
Zucchini |
Refined
Sugar
Most cold cereals (e.g., Grape Nuts, Corn Flakes, Raisin
Bran, etc.)
Rice Cakes
Granola |
Bagel
Bread (white flour)
Carrots
Corn
Granola Bar
Kidney Beans
Muffin (bran)
Potato
Pretzels
Rice
Tortilla |
Oatmeal
Pasta
Peas
Pita Bread
Pinto Beans
Rye Bread
Whole Grain Breads
Yams |
Lentils
Nuts
Seeds |
The Glycemic Load
One of the shortcomings of the glycemic index is that it only tells
us about the quality of the carbohydrates, not the quantity. Obviously,
quantity matters too, but the measurement of the glycemic index
of a food is not related to portion size. That is where the glycemic
load (GL) comes into play. The GL is a relatively new way to assess
the impact of carbohydrate consumption that takes the glycemic index
into account, but provides much more accurate information than the
glycemic index alone. A GI value tells you only how rapidly a particular
carbohydrate source turns into blood sugar. It doesn't tell you
how much of that carbohydrate is in a serving of a particular food.
You need to know both things to understand a food's effect on blood
sugar.
For instance, watermelon has a GI of 72 compared to glucose, but
the amount of carbohydrate in a 1/2 cup of is only 6 grams. The
GL calculated by multiplying the amount of carbohydrate in a serving
of food multiplied by that food's GI (as compared to glucose) as
a decimal. Therefore, to calculate the GL for a 1/2 cup serving
of watermelon we would multiply 12 times 72 to equal a GL of 4.3.
Compare this to 1/2 cup of Grape Nuts(tm) that also has a GI of
71 and but provides 47 grams of carbohydrate yielding a whopping
GL of 33 or 1 cup of white rice that also has GI of 72, but provides
36 grams of carbohydrate so its GL is 26. So, while the GI is important
it is not as critical as the GL. A GL of 20 or more is regarded
as high, a GL of 11 to 19 is medium, and a GL of 10 or less is low.
The higher the GL the greater the stress on insulin.
Table 2 -
Examples of GI, GL, and insulin stress scores of selected foods
| Food |
GI |
GL |
Insulin Stress |
| Carrots, cooked, 1/2 cup |
49 |
1.5 |
low |
| Peach, fresh, 1 large |
42 |
3 |
low |
| Watermelon, 1/2 cup |
72 |
4 |
low |
| Wholewheat bread, 1 slice |
69 |
9.6 |
low |
| Baked potato, medium |
93 |
14 |
medium |
| Brown rice, cooked, 1 cup |
50 |
16 |
medium |
| Banana, raw, 1 medium |
55 |
17.6 |
medium |
| Spaghetti, white, cooked, 1 cup |
41 |
23 |
high |
| White rice, cooked, 1 cup |
72 |
23 |
high |
| Grape Nuts(tm), 1/2 cup |
71 |
33 |
very high |
| Soft drinks, 375 ml |
68 |
34.7 |
very high |
Clinical Research with the Glycemic
Load
Research studies are just starting to utilize the GL as a more
sensitive marker for the role of diet in chronic diseases like diabetes
and heart disease. The preliminary results are showing an even stronger
link in predicting chronic disease than the GI. For example, when
researchers from the Nurses Health Study used GL measures to assess
the impact of carbohydrate consumption on women they found that
high-GL diets (and, by extension, high GI foods and greater total
carbohydrate intake), correlated with even more significantly greater
risk for heart disease than the GI because of lower levels of protective
HDL-cholesterol and higher triglyceride levels.
Key References:
- Leeds AR. Glycemic index and heart disease. Am J Clin Nutr
2002;76:286S-9S.
- Wolever TM, Mehling C. High-carbohydrate-low-glycaemic index
dietary advice improves glucose disposition index in subjects
with impaired glucose tolerance. Br J Nutr 2002;87:477-87.
- Fung TT, Hu FB, Pereira MA, et al. Whole-grain intake and the
risk of type 2 diabetes: a prospective study in men. Am J Clin
Nutr 2002;76:535-40.
- Willett W. Manson J, Liu S. Glycemic index, glycemic load,
and risk of type 2 diabetes. Am J Clin Nutr 2002;76(Suppl.)274S-80S.
- Liu S, Willett WC, Stampfer MJ, Hu FB, et al. A prospective
study of dietary glycemic load, carbohydrate intake, and risk
of coronary heart disease in US women. Am J Clin Nutr 2000;71:1455-61.
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