| PharmaGABA: Natural Support for Stress, Anxiety,
and Insomnia
Introduction
Everyday stress is a normal part of modern living. Job pressures; family
arguments; financial pressures; traffic, and time management are just
a few of the "stressors" we are faced with on a daily basis.
For some people, the stress can be overwhelming leading to feelings of
anxiety and insomnia. Fortunately, there is PharmaGaba - a safe and effective
natural remedy that has just been introduced to North America.
PharmaGABA: Natural promotion of a relaxed
state
GABA (gamma-aminobutyric acid) is a natural calming and anti-epileptic
agent in the brain. In fact, it is one of the brain’s most important
regulators of proper function and neurotransmitter. It appears that many
people with anxiety, insomnia, epilepsy, and other brain disorders do
not manufacture sufficient levels of GABA.1 Many popular
drugs such as Valium, Neurontin, baclofen, and Valproate act by increasing
the effects of GABA within the brain. However, while these drugs have
numerous side effects and are highly addictive drugs not suitable for
long-term use, GABA in the right form is completely safe and remarkably
effective without side effects.
Studies with synthetic GABA have shown that it does not cross the blood-brain
barrier very well. That led to the assumption that virtually all of the
GABA found in the brain is manufactured there and that supplemental GABA
would not increase levels of GABA in the brain. That appears to be the
case with synthetic GABA, but not with natural GABA in the form of PharmaGABA
- a special form of GABA naturally manufactured from Lactobacillus hilgardii
– the bacteria used to ferment vegetables in the preparation of
the traditional Korean dish known as kimchi.
PharmaGaba increases alpha-wave production
by the brain
Unlike chemically produced, synthetic GABA, natural PharmaGABA appears
to be able to cross the blood brain barrier to produce relaxation. Research
has shown that PharmaGABA increases the production of alpha brain waves
(a state often achieved by meditation and characterized by being relaxed
with greater mental focus and mental alertness) as well as reduce beta-waves
(associated with nervousness, scattered thoughts, and hyperactivity).
PharmaGABA is approved for use in Japan as an aid to conquer stress and
promote relaxation. It is a very is a popular ingredient in function foods
and beverages as well as dietary supplements designed to produce mental
and physical relaxation, without inducing drowsiness. The most popular
applications of PharmaGABA is in chocolate and coffee beverages. It is
particularly helpful in counteracting the effects of caffeine.
PharmaGABA is fast-acting, especially when it is taken in a chewable tablet.
Generally, the effects are felt within the first 15 minutes, and have
been shown to last up to 4 to 6 hours.
PharmaGABA is clinically proven
Clinical studies with PharmaGABA have yielded some very interesting results.2
For example, one study had subjects who were afraid of heights transverse
a long walking suspension bridge that spanned a 150 foot canyon. Halfway
across the bridge a saliva sample was obtained and blood pressure was
determined. What the researchers were looking for in the saliva was the
level of secretory IgA – an important antibody in saliva that helps
fight infection. Typically, during times of stress saliva levels drop,
sometimes quite precipitously. This event happened when the subjects were
given a placebo, but when they were given PharmaGABA the secretory IgA
levels in the saliva were maintained halfway across the bridge and actually
increased upon completion of the crossing.
| Illustration: Walking across this suspension bridge is enough to
give anyone a bit of anxiety. When subjects with a fear of heights
were given PharmaGABA they actually experienced a relaxed state at
the halfway point across the bridge. Click HERE
for larger picture. |
Another study with PharmaGABA demonstrated an impressive
ability to improve sleep quality. The ability to feel refreshed and ready
to tackle the day requires us to achieve deep levels of sleep and to stay
in this deep sleep for sufficient time. Unfortunately, many people do
not achieve these deep levels of sleep and conventional sleeping pills
actually inhibit deep levels of sleep and disrupt normal sleep patterns
causing people to wake up feeling more tired when they went to bed. That
is definitely not the case with PharmaGABA.
Dosage recommendations
PharmaGABA can be used whenever someone feels a bit “stressed out.”
For best results use it in a chewable tablet form at dosage of 100 to
200 mg up to three times daily. To promote a better night’s sleep
take 200 to 300 mg at bedtime. PharmaGABA is completely safe and without
any known adverse drug interaction, as a general guideline it is recommended
to take no more than 600 mg within a 6 hour period and no more than 1,200
mg within a 24 hour period.
Key references:
- J. Krystal, Sanacora G, Blumberg H, et al. Glutamate and GABA systems
as targets for novel antidepressant and mood-stabilizing treatments,
Mol Psychiatr 2002;7:S71–S80.
- Abdoua AM; Higashiguchia S, Horiea K, et al. Relaxation and immunity
enhancement effects of Gamma-Aminobutyric acid (GABA) administration
in humans. BioFactors 2006;26:201–208.
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