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Question:
Does supplementing with DHEA increase my risk for prostate cancer?
Answer:
Probably not. If a significant portion of DHEA is converted to testosterone it is certainly possible that it might increase the risk for prostate cancer, but when DHEA is used at a reasonable dosage it does not appear to raise testosterone levels. If DHEA is not turned into testosterone, it is not likely to be a problem as in test tube studies DHEA has been shown to actually decrease prostate cancer cell growth and studies looking at blood levels of DHEA in men with prostate cancer showed no relationship.
Until the question of DHEA and prostate cancer is more adequately answered it seems wise for men with a history of prostate cancer to avoid DHEA supplementation or use it at reasonable dosages with close monitoring of the prostate specific antigen (PSA) – a blood marker of prostate cancer. An alternative is to use a form of DHEA known as 7-Keto DHEA because this form can not be converted to testosterone.
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