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Question:
I have heard that vitamin B2 can help with migraine headaches. Is there any truth to this recommendation?
Answer:
Yes. One of the theories used to explain what causes a migraine headache is that they are caused by a reduction of energy production within the energy producing units of cells (the mitochondria) of blood vessels in the head. Therefore, because vitamin B2 (riboflavin) has the potential of increasing cellular energy production it was thought that it might have preventive effects against migraine. A preliminary study showed excellent results with high-dose riboflavin therapy. To further determine the effectiveness of high-dose riboflavin therapy, a recent double-blind study compared riboflavin (400 mg daily) and placebo in 55 patients with migraine in a three month trial. Riboflavin was superior to placebo in reducing attack frequency and headache days. The proportion of patients who improved by at least 50% was 15% for placebo and 59% for riboflavin. There were no side effects attributed to the riboflavin therapy.
The results of these preliminary studies makes high-dose riboflavin therapy an attractive option as a preventive measure against migraine headaches because of its high efficacy, excellent tolerability, and low cost.
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Also See:
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